主要论文著作(#为共同第一作者, *为通讯作者) 1. L. Niu, Y. Jia, M. Wu, H. Liu, Y. Hong, Y. Hu, X. Zhang, D. Gao, F. Xu, G. Huang*. Matrix stiffness controls cardiac fibroblast differentiation through regulating YAP via AT1R. Journal of Cellular Physiology, 235(11): 8345-8357, 2020 2. H. Liu#, M. Wu#, Y. Jia, L. Niu, G. Huang*, F. Xu*. The shape of fibroblasts regulates their responses to mechanical and biochemical cues in three dimensions. NPG Asia Materials, 12(1): 45, 2020 3. W. Zhang, G. Huang*, F. Xu. Engineering biomaterials and approaches for mechanical stretching of cells in three dimensions. Frontiers in Bioengineering and Biotechnology, 8: 589590, 2020 4. B. Cheng#, W. Wan#, G. Huang, Y. Li, G.M. Genin, M.R.K. Mofrad, T.J. Lu, F. Xu, M. Lin*. Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation. Science Advances, 6(10): eaax1909, 2020 5. G. Jin, W. Li, F. Song, J. Zhao, M. Wang, Q. Liu, A. Li, G. Huang and F. Xu*. Fluorescent conjugated polymer nanovector for in vivo tracking and regulating the fate of stem cells for restoring infarcted myocardium. Acta Biomaterialia, 109: 195-207, 2020 6. G. Zhao, X. Zhang, B. Li, G. Huang, F. Xu, X. Zhang*. Solvent-Free Fabrication of carbon nanotube/silk fibroin electrospun matrices for enhancing cardiomyocyte functionalities. ACS Biomaterials Science & Engineering, 6(3): 1630–1640, 2020 7. M. Wang, B. Cheng, Y. Yang, H. Liu, G. Huang, L. Han, F. Li*, F. Xu*. Microchannel stiffness and confinement jointly induce the mesenchymal-amoeboid transition of cancer cell migration. Nano Letters, 19: 5949−5958, 2019 8. G. Zhao#, X. Bao#, G. Huang, F. Xu*, X. Zhang*. Differential effects of directional cyclic stretching on the functionalities of engineered cardiac tissues. ACS Applied Bio Materials, 2(8): 3508-3519, 2019 9. Y. Ji#, Q. Yang#, G. Huang, M. Shen, Z. Jian, M.J. Thoraval, Q. Lian, X. Zhang*, F. Xu*. Improved resolution and fidelity of droplet-based bioprinting by upward ejection. ACS Biomaterials Science & Engineering, 5(8): 4112-4121, 2019 10. G. Huang, F. Xu, G.M. Genin, T.J. Lu*. Mechanical microenvironments of living cells: a critical frontier in mechanobiology. Acta Mechanica Sinica, 35(2): 265-269, 2019 11. J. Tian#, G. Huang#, M. Lin, J. Qiu, B. Sha, T.J. Lu*, F. Xu*. A mechanoelectrical coupling model of neurons under stretching. Journal of the Mechanical Behavior of Biomedical Materials, 93: 213-221, 2019 12. H. Qing#, G. Jin#, G. Zhao, G. Huang, Y. Ma, X. Zhang, B. Sha, Z. Luo, T.J. Lu*, F. Xu*. Heterostructured silk-nanofiber-reduced graphene oxide composite scaffold for SH-SY5Y cell alignment and differentiation. ACS Applied Materials & Interfaces, 10(15), 39228–39237, 2018 13. G. Zhao, H. Qing, G. Huang, G.M. Genin, T.J. Lu, Z. Luo, F. Xu*, X. Zhang*. Reduced graphene oxide functionalized nanofibrous silk fibroin matrices for engineering excitable tissues. NPG Asia Materials, 10, 982-994, 2018 14. C. Ji#, F. Song#, G. Huang#, S. Wang, H. Liu, S. Liu, L. Huang, S. Liu, J. Zhao, T.J. Lu*, F. Xu*. The protective effects of acupoint gel embedding on rats with myocardial ischemia-reperfusion injury. Life Sciences, 211: 51-62, 2018 15. Y. Ma#, M. Lin#, G. Huang, Y. Li, S. Wang, H. Yang, A. Li, T. J. Lu, F. Xu*. Three-dimensional spatiotemporal mechanical microenvironment: a hydrogel-based platform for guiding stem cell fate. Advanced Materials, 1705911, 2018 16. 徐峰, 张晓慧*, 鲍雪娇, 赵国旭, 刘付生, 黄国友, 李昱辉和卢天健. 基于先进生物材料的心肌细胞力–电微环境体外构建. 力学进展, 48: 320-359, 2018 17. W. Zhang, G. Huang*, K. Ng, Y. Ji, B. Gao, Q. Huang, J. Zhou, T.J. Lu, F. Xu. Engineering ellipsoidal cap-like hydrogel particles as building blocks or sacrificial templates for three-dimensional cell culture. Biomaterials Science, 6(4): 885-892, 2018 18. 胡焱, 洪源, 师念园, 黄国友和赵昕*. 基于甲基丙烯酸酯明胶的神经干细胞三维微环境的构建调控. 中国科技论文, 12(24): 2770-2776, 2017 19. G. Huang#, F. Li#, X. Zhao, Y. Ma, Y. Li, M. Lin, G. Jin, T.J. Lu, G.M. Genin and F. Xu*. Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment. Chemical Reviews, 117(20): 12764-12850, 2017 20. B. Cheng, M. Lin, G. Huang, Y.H. Li, B.H. Ji, G.M. Genin, V.S. Deshpande, T.J. Lu and F. Xu*. Energetics: An emerging frontier in cellular mechanosensing: Reply to comments on “Cellular mechanosensing of the biophysical microenvironment: A review of mathematical models of biophysical regulation of cell responses”. Physics of Life Reviews, 22-23: 130-135, 2017 21. B. Cheng, M. Lin, G. Huang, Y.H. Li, B.H. Ji, G.M. Genin, V.S. Deshpande, T.J. Lu and F. Xu*. Cellular mechanosensing of the biophysical microenvironment: A review of mathematical models of biophysical regulation of cell responses. Physics of Life Reviews, 22-23: 88-119, 2017 22. Y.L. Han#, M.X. Li#, Q.Z. Yang#, G. Huang, H. Liu, Y.D. Qin, G.M. Genin, T.J. Lu* and F. Xu*. Collective wetting of a natural fibrous system and its application in pump-free droplet transfer. Advanced Functional Materials, 27(22): 1606607, 2017 23. G. Huang, M.X. Li, Q.Z. Yang, Y.H. Li, H. Liu, H. Yang and F. Xu*. Magnetically actuated droplet manipulation and its potential biomedical applications. ACS Applied Materials & Interfaces, 9(2): 1155-1166, 2017 24. B. Cheng, M. Lin, Y.H. Li, G. Huang, H. Yang, Guy M. Genin, Vikram S. Deshpande, T.J. Lu and F. Xu*. An integrated stochastic model of matrix-stiffness-dependent filopodial dynamics. Biophysical Journal, 111(9): 2051-2061, 2016 25. K.W. Yong, Y.H. Li, F.S. Liu, B. Gao, T.J. Lu, W.A.B. Wan Abas, W.K.Z. Wan Safwani, B. Pingguan-Murphy, Y. Ma, F. Xu and G. Huang*. Paracrine effects of adipose-derived stem cells on matrix stiffness-induced cardiac myofibroblast differentiation via angiotensin II type 1 receptor and Smad7. Scientific Reports, 6: 33067, 2016 26. G. Huang, L.M. Tian, K.-K. Liu, B. Hu, F. Xu, T.J. Lu, R.R. Naik and S. Singamaneni*. Elastoplastic deformation of silk micro- and nanostructures. ACS Biomaterials Science & Engineering, 2(6): 893-899, 2016 27. Y.H. Li#, G. Huang#, M. Li, L. Wang, E.L. Elson, T. J. Lu, G.M. Genin* and F. Xu*. An approach to quantifying 3D responses of cells to extreme strain. Scientific Reports, 6: 19550, 2016 28. Y.H. Li, G. Huang*, B. Gao, M.X. Li, G.M. Genin, T.J. Lu and F. Xu*. Magnetically-actuated cell-laden microscale hydrogels for probing strain-induced cell responses in three dimensions. NPG Asia Materials, 8: e238, 2016 29. H. Qi*, G. Huang, Y.L. Han, L. Wang*, S.Q. Wang, T.J. Lu and F. Xu. In vitro spatially organizing the differentiation in individual multicellular stem cell aggregates. Critical Reviews in Biotechnology, 36(1): 20-31, 2016 30. L. Wang#, Y.H. Li#, G. Huang, X. Zhang, B. Pingguan-Murphy, B. Gao, T.J. Lu and F. Xu*. Hydrogel-based methods for engineering cellular microenvironment with spatiotemporal gradients. Critical Reviews in Biotechnology, 36(3): 553-565, 2016 31. Q.C. Zhang, X. Yang, P. Li, G. Huang, S. Feng, C. Shen, B. Han, X. Zhang, F. Jin, F. Xu* and T.J. Lu*. Bioinspired engineering of honeycomb structure – Using nature to inspire human innovation. Progress in Materials Science, 74: 332-400, 2015 32. K.W. Yong, Y.H. Li, G. Huang, T.J. Lu, W.K.Z. Wan Safwani, B. Pingguan-Murphy and F. Xu*. Mechano-regulation of cardiac myofibroblast differentiation: Implications for cardiac fibrosis and therapy. American Journal of Physiology-Heart and Circulatory Physiology, 309(4): H532-H542, 2015 33. D.T. Chong, X.S. Liu, H.J. Ma, G. Huang, Y.L. Han, X.Y. Cui, J.J. Yan and F. Xu*. Advances in fabricating double-emulsion and their biomedical applications. Microfluidics and Nanofluidics, 19(5): 1071-1090, 2015 34. Y.F. Ma, Y. Ji, G. Huang, K. Ling, X.H. Zhang* and F. Xu*. Bioprinting 3D cell-laden hydrogel microarray for screening human periodontal ligament stem cells response to extracellular matrix. Biofabrication, 7(4): 044105, 2015 35. K. Ling, G. Huang, J. Liu, X. Zhang, Y. Ma, T.J. Lu* and F. Xu*. Bioprinting-based high-throughput fabrication of three-dimensional MCF-7 human breast cancer cellular spheroids. Engineering, 1(2): 269-274, 2015 36. F.S. Liu, C.H. Li, S.B. Liu, G.M. Genin, G. Huang, T.J. Lu* and F. Xu*. Effect of viscoelasticity on skin pain sensation. Theoretical and Applied Mechanics Letters, 5(6): 222-226, 2015 37. L. Wang, M. Qiu, Q. Yang, Y. Li, G. Huang, M. Lin, T.J. Lu and F. Xu*. Fabrication of microscale hydrogels with tailored microstructures based on liquid bridge phenomenon. ACS Applied Materials & Interfaces, 7: 11134-11140, 2015 38. Z. Liu, Z. Wei, X.L. Zhu, G. Huang, F. Xu, J.H. Yang, Y. Osada, M. Zrínyi, J.H. Li* and Y.M. Chen*. Dextran-based hydrogel formed by thiol-Michael addition reaction for 3D cell encapsulation. Colloids and Surfaces B: Biointerfaces, 128: 140-148, 2015 39. S. Liu#, P. Wang#, G. Huang, L. Wang, J. Zhou, T.J. Lu, F. Xu and M. Lin*. Reaction-induced swelling of ionic gels. Soft Matter, 11(3): 449-455, 2015 40. 刘灏, 黄国友*, 李昱辉, 张晓慧, 卢天健和徐峰*. 基于水凝胶的“自下而上”组织工程技术研究进展. 中国科学-生命科学, 45(3): 256-270, 2015 41. Y.H. Li#, G. Huang#, X.H. Zhang, L. Wang, Y.N. Du, T.J. Lu and F. Xu*. Engineering cell alignment in vitro. Biotechnology Advances, 32: 347–365, 2014 42. H. Qi, G. Huang, Y.L. Han, Y.H. Li, X.H. Zhang, B. Pingguan-Murphy, T.J. Lu, F. Xu and L. Wang. Engineering artificial machines from designable DNA materials for biomedical applications. Tissue Engineering Part B: Reviews, 21(3): 288-297, 2014 43. L. Wang#, G. Huang#,*, B.Y. Sha, S.Q. Wang, Y.L. Han, J.H. Wu, T.J. Lu and F. Xu*. Engineering three-dimensional cardiac microtissues for potential drug screening applications. Current Medicinal Chemistry, 21(22): 2497-2509, 2014 44. Y. Han#, S. Wang#, X.H. Zhang, Y.H. Li, G. Huang, H. Qi, B. Pingguan-Murphy, Y.H. Li, T.J. Lu* and F. Xu*. Engineering physical microenvironment for stem cell based regenerative medicine. Drug Discovery Today, 16: 763-773, 2014 45. Y.L. Han, W.Q. Wang, J. Hu, G. Huang, S.Q. Wang, W.G. Lee, T.J. Lu* and F. Xu*. Benchtop fabrication of three-dimensional reconfigurable microfluidic device from paper/polymer composite, Lab on a Chip, 3(24): 4745-4749, 2013 46. X. He, P.F. Wang, G. Huang, S.B. Liu, M.L. Xu, F. Xu, T.J. Lu, Development of a micro-indentation device for measuring the mechanical properties of soft materials. Theoretical & Applied Mechanics Letters, 3(5): 054004, 2013 47. Y.H. Li#, G. Huang#, X.H. Zhang, B.Q. Li, Y.M. Chen, T.L. Lu, T.J. Lu* and F. Xu*. Magnetic hydrogels and their potential biomedical applications, Advanced Functional Materials, 23(6): 660-672, 2013 48. G. Huang, S.H. Wang, X. He, X.H. Zhang, T.J. Lu* and F. Xu*. Helical spring template fabrication of cell-laden microfluidic hydrogels for tissue engineering. Biotechnology & Bioengineering, 110(3): 980-989, 2013 49. G. Huang, X.H. Zhang, Z.P. Xiao, Q.C. Zhang, J.X. Zhou, F. Xu* and T.J. Lu*. Cell-encapsulating microfluidic hydrogels with enhanced mechanical stability. Soft Matter, 8(41): 10687-10694, 2012 50. G. Huang#, L. Wang#, S.Q. Wang, Y.L. Han, J.H. Wu, Q.C. Zhang, F. Xu* and T.J. Lu*. Engineering three-dimensional cell mechanical microenvironment with hydrogels. Biofabrication, 4(4): 042001, 2012 51. Y. Fan#, F. Xu#,*, G. Huang, T.J. Lu and W.L. Xing*. Single neuron capture and axonal development in three-dimensional microscale hydrogels. Lab on a Chip, 12(22): 4724-4731, 2012 52. G. Huang#, L.H. Zhou#, Q.C. Zhang, Y.M. Chen, W. Sun, F. Xu* and T.J. Lu*. Microfluidic hydrogels for tissue engineering. Biofabrication, 3(1): 012001, 2011 53. L.H. Zhou, G. Huang, S.Q. Wang, J.H. Wu, W.G. Lee, Y.M. Chen, F. Xu* and T.J. Lu*. Advances in cell-based biosensors using three-dimensional cell-encapsulating hydrogels, Biotechnology Journal, 6(12): 1466-1476, 2011 54. J.X. Zhou, G. Huang, M.E. Li and A.K. Soh*. Stress evolution in a phase-separating polymeric gel. Modelling and Simulation in Materials Science and Engineering, 18(2): 025002, 2010 55. 黄国友, 徐峰, 周丽宏, 周进雄, 陈咏梅和卢天健*. 载细胞水凝胶体系中微通道结构对营养物输送能力的影响. 西安交通大学学报, 45(4): 115-120, 2010 56. 周丽宏, 陈自强, 黄国友, 翟晓, 陈咏梅, 徐峰和卢天健*. 细胞打印技术及应用. 中国生物工程杂志, 30(12): 95-104, 2010 专利 1. 沙保勇,黄国友,徐峰,“磁控高通量药物筛选血脑屏障模拟装置”,中国发明专利,2017.12.19,专利号:ZL201720392842.5 2. 徐峰,黄国友,凌楷和卢天健, “一种基于水凝胶微孔板的细胞球原位制备方法”,中国发明专利,2017.06.06,专利号:ZL201510025985.8 3. 徐峰,何翔,王琳,王鹏飞,黄国友和卢天健,“多层PEG-DMA水凝胶的制备方法”,中国发明专利,2015.07.15,专利号:ZL201310722478.0 4. 黄国友,卢天健,徐峰和周丽宏,“一种力学增强型载细胞微通道水凝胶的制备方法”,中国发明专利,2013.10.16,专利号:ZL201110215024.5 5. 黄国友,卢天健,徐峰和周丽宏,“一种基于蔗糖纤维模板的载细胞微通道水凝胶的制备方法”,中国发明专利,2013.07.10,专利号:ZL201110213980.x 6. 徐峰,卢天健和黄国友,“一种基于活细胞的复杂三维微通道多孔支架的制备方法”,中国发明专利,2013.10.16,专利号:ZL201110259019.4 |